Building a more equitable economy and closing the gap in the “tale of two cities” are core objectives of Mayor de Blasio’s economic development policies. A key component of that progressive economic agenda is fostering a vibrant industrial sector for New York City by retaining the city’s existing industrial base and capitalizing on New York’s innovation economy to drive new industrial growth. This paper calls on the mayor to implement a plan to create 50,000 new quality manufacturing and industrial jobs in the next ten years, and lays out the comprehensive zoning, financing, and other programmatic steps that will achieve that goal.